Active — Not RecruitingNot Applicable

Change in Sleep Breathing During Hospital Admission for COPD Exacerbation

France60 participantsStarted 2025-12-09

Plain-language summary

hronic obstructive pulmonary disease (COPD) is a common lung disease that can worsen suddenly, leading to hospital admission. During these exacerbations, breathing becomes unstable and recovery is difficult to predict. Currently, doctors lack simple tools to monitor how patients recover day by day during hospitalization and after discharge. This observational study aims to describe how breathing patterns during sleep change over time in patients hospitalized for a COPD exacerbation. Breathing will be monitored using standard sleep recordings and a non-contact sensor placed under the mattress, which measures breathing without disturbing the patient. By better understanding how nocturnal breathing variability evolves during recovery, this study may help identify early signs of improvement or deterioration, support safer hospital discharge decisions, and improve follow-up after hospitalization for COPD exacerbation

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria * Adults (≥ 18 years) with a confirmed diagnosis of chronic obstructive pulmonary disease (COPD) based on spirometry * Hospitalized for an acute exacerbation of COPD for less than 24 hours at the time of inclusion * Admitted to an acute medical ward * Able to provide written informed consent * Affiliated with the national health insurance system Exclusion Criteria * Ongoing invasive or non-invasive mechanical ventilation at the time of inclusion * Long-term non-invasive ventilation or positive airway pressure therapy prior to hospitalization * Use of an anti-pressure (anti-decubitus) mattress incompatible with the study devices * Severe anxiety disorders interfering with study procedures * Known allergy to materials used for sensor placement * Pregnancy or breastfeeding * Minor or legally protected adult (guardianship, curatorship) or deprivation of liberty * Lack of health insurance coverage

What they're measuring

Nocturnal ventilatory variability during sleep assessed by polysomnography

Timeframe: Baseline (first night after hospitalization), Day 3 of hospitalization, Day 7 of hospitalization or the day before discharge (if discharge occurs earlier), and 6 weeks after hospital discharge (study completion)

Trial details

NCT IDNCT07361744

SponsorAsten Sante

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2027-04-01