Herpes zoster is caused by the reactivation of latent varicella-zoster virus (VZV) which stays in latency after its primary infection. Immunosenescence contributes significantly to elevating morbidity associated with aging. Vaccination plays a key role in reducing the disease burden of zoster and the associated complications. We are conducting a study entitled "A Randomized, Blinded, Placebo- and Active-Controlled, Adaptive Phase 2 Clinical Trial to Evaluate the Immunogenicity and Safety of SYS6017 (a Herpes Zoster mRNA Vaccine) in Healthy Participants Aged 40 Years and Above".
Age range
40 Years
Sex
ALL
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Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
solicited adverse events
Timeframe: within 14 days post each vaccination
unsolicited adverse events
Timeframe: within 30 days post each vaccination
Geometric Mean Concentration (GMC) of anti-gE antibody
Timeframe: On Day 14 and Day 30 after the completion of the full vaccination course
Geometric Mean Fold Increase (GMFI) of anti-gE antibody
Timeframe: On Day 14 and Day 30 after the completion of the full vaccination course
Seroconversion Rate (SCR) of anti-gE antibody
Timeframe: On Day 14 and Day 30 after the completion of the full vaccination course
Clinical Trials Information Group officer