Not Yet RecruitingNot Applicable

Undiluted and Diluted Nutrition

Poland80 participantsStarted 2026-02-02

Plain-language summary

Adult patients after elective major abdominal surgeries who are planned to be admitted to the Intensive Care Unit (ICU) can be included in the trial. Each patient will be fed via the gastrointestinal tract. Half of the patients will receive enteral nutrition (EN) with additional fluids, and the rest will receive undiluted EN. The primary aim of this study is to assess feeding intolerance in both patient groups.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Adults, ≥18, Scheduled for major abdominal surgery requiring ICU admission Having access to the GI tract (gastric or jejunal) Planned to be fed enterally Exclusion Criteria: Patients unable to give informed consent After emergency surgeries Without access to the GI tract Individuals with contraindications to EN, such as short bowel syndrome, uncompensated shock, acidosis (pH \< 7.1; lactate \> 5 mmol/l), bleeding from the upper GI tract, obstruction, intestinal ischemia, abdominal compartment syndrome Patients with symptomatic gastro-esophageal reflux Expected ICU stay \< 3 days Pregnancy and lactation

What they're measuring

Number of patients having vomiting.

Timeframe: From the date of randomization until the date of the ICU discharge or death but no longer than 8 weeks, whichever came first

Number of participants who received prokinetic agents.

Timeframe: From the date of randomization until the date of the ICU discharge or death but no longer than 8 weeks, whichever came first

Trial details

NCT IDNCT07352150

SponsorJohn Paul II Catholic University of Lublin

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-06-30

Contact for this trial

Michal Borys

+48506350569 michal.borys@kul.pl

View on ClinicalTrials.gov More Critical Illness trials

Plain-language summary

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Number of patients having vomiting.

Timeframe: From the date of randomization until the date of the ICU discharge or death but no longer than 8 weeks, whichever came first

Number of participants who received prokinetic agents.

Timeframe: From the date of randomization until the date of the ICU discharge or death but no longer than 8 weeks, whichever came first