Intensive Versus Conventional Blood Pressure Control Following Stroke Thrombectomy

Inclusion Criteria: * Age ≥ 18 years * To receive endovascular thrombectomy \<24 hours after the onset of symptoms * Diagnosed with acute anterior circulation ischemic stroke * National Institutes of Health Stroke Scale (NIHSS) score ≤ 30; * Alberta Stroke Program Early CT Score (ASPECTS) ≥ 6 * Computed Tomography Angiography (CTA), Magnetic Resonance Angiography (MRA), or Digital Subtraction Angiography (DSA) confirming occlusion of the intracranial internal carotid artery or M1/M2 segment of the middle cerebral artery * Successful recanalization of the occluded vessel without in-situ or proximal stenosis (modified Treatment in Cerebral Infarction, mTICI ≥ 2b) * Sustained elevated systolic blood pressure (≥140 mmHg for at least two consecutive measurements, separated by \>10 minutes) within 3 hours of reperfusion * Written informed consent provided by the patient or their legal representative Exclusion Criteria: * Pre-existing stroke disability defined by a modified Rankin score (mRS) \>2 * Unlikely to benefit from or tolerate endovascular thrombectomy, such as severe allergic reaction to contrast agents * Failure to achieve mTICI ≥ 2b with endovascular intervention, or presence of in situ or proximal vascular stenosis * Patients with contraindications for the use of antihypertensive medications, such as allergy to components * Intracranial space-occupying lesions, including brain tumors and vascular malformations * Patients with severe liver or renal dysfunction, or thos…