Safety and Food Effect on Single-Dose Bioavailability of F-02-2-Na in Healthy Adult Subjects

Inclusion Criteria: * 1\. The subjects should fully understand the purpose, nature, process of the study and the possible adverse reactions, voluntarily act as subjects, and sign the informed consent form before the start of any research procedures. * 2\. Healthy male or female subjects aged 18 to 45 years old (inclusive). * 3\. The body weight for male and female subjects should be ≥ 50.0 kg and ≥ 45.0 kg, respectively; the body mass index (BMI) should be between 19 kg/m² and 26 kg/m² (inclusive). * 4\. The subjects should have normal results or abnormal results without clinical significance in vital signs check, physical examination, clinical laboratory tests (Complete Blood Count (CBC), urine analysis, blood biochemistry, coagulation panel, free thyroid function tests), chest X-ray, liver and renal color ultrasound and 12-lead electrocardiogram. * 5\. Normal renal function as determined by Investigator following review of clinical laboratory test results, including eGFR ≥ 90 mL/min/1.73 m². * 6\. The subjects (including male subjects) should have no plans for having children from screening until 6 months after the last dose and should voluntarily take effective contraceptive measures and have no plans for sperm or egg donation. * 7\. The subjects should be able to communicate well with the researchers and understand and comply with the requirements of this study. Exclusion Criteria: * 1\. Subjects with a specific allergic history (such as asthma, urticaria, eczema, etc.…