The Efficacy and Safety of Anti-inflammation Treatment (Hirudoid Introduction Followed by Yellow … (NCT07343635) | Clinical Trial Compass
RecruitingNot Applicable
The Efficacy and Safety of Anti-inflammation Treatment (Hirudoid Introduction Followed by Yellow Light Therapy) Combined With Tofacitinib and Doxycycline in Chinese Adult Patients With Mild to Moderate Erythematous Telangiectatic Rosacea
China186 participantsStarted 2026-02-01
Plain-language summary
The efficacy and safety of anti-inflammation treatment (Hirudoid introduction followed by yellow light therapy) combined with tofacitinib and doxycycline in Chinese adult patients with mild to moderate erythematous telangiectatic rosacea: A prospective parallel controlled single-blind cohort study
Who can participate
Age range18 Years – 70 Years
SexALL
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Inclusion Criteria:
* The subjects are male or female, aged 18 to 70 years (inclusive); they voluntarily participate in this study and sign the informed consent form.
* They are diagnosed with erythematous telangiectatic rosacea, meeting the diagnostic criteria in the "Chinese Guidelines for the Diagnosis and Treatment of Rosacea (2021)".
* At screening and baseline, the IGA score is 2 (mild) or 3 (moderate).
* The subjects agree not to use any other rosacea treatment drugs (prescription or over-the-counter) during the study period.
* The subjects are willing to minimize external factors that may trigger rosacea (such as spicy food, alcoholic beverages, prolonged sun exposure, etc.).
* The subjects (including their partners) agree that they have no plans to conceive within 3 months after signing the informed consent form until the end of the last treatment and are willing to take effective contraceptive measures voluntarily.
Exclusion Criteria:
* Diagnosed as papulopustular, hypertrophic, ocular rosacea or other special types of rosacea
* Other facial skin diseases that were active during the screening period or baseline may interfere with the efficacy/safety assessment of erythematous vasodilating rosacea, including but not limited to perioral dermatitis, facial keratosis, seborrheic dermatitis, and acne vulgaris. If the above-mentioned skin diseases were in clinical remission both during the screening period and at baseline, and the investigators determined that they wou…
What they're measuring
1
Achievement of IGA treatment success at Week 12
Timeframe: 0 week、12 week
Trial details
NCT IDNCT07343635
SponsorThe Fourth Affiliated Hospital of Zhejiang University School of Medicine