RecruitingPhase 1

A Phase 1 Clinical Trial to Evaluate the Safety and DDI of DW4421 and 3 NSAIDs

South Korea150 participantsStarted 2025-12-01

Plain-language summary

Drug-Drug Interaction between DW4421 and three different kinds of NSAIDs

Who can participate

Age range19 Years – 50 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy adult aged 19 to 50 (inclusive) years, at the time of screening. * Subjects weighing between 50 kg and 90 kg with BMI between 18 and 27 kg/m2 (inclusive) at screening visit. Exclusion Criteria: * Those who have clinical significant liver, kidney, nervous system, respiratory, endocrine, hematology and oncology, cardiovascular, urinary, and mental diseases or past history

What they're measuring

Cmax,ss

Timeframe: Baseline to Day 13 or Day 15

AUCτ,ss

Timeframe: Baseline to Day 13 or Day 15

Trial details

NCT IDNCT07343245

SponsorDaewon Pharmaceutical Co., Ltd.

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2026-02-22

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