CompletedNot Applicable

Exercise-Modulated Cognitive Hormones

Saudi Arabia60 participantsStarted 2025-06-15

Plain-language summary

Investigating the influence of a 12-week exercise regimen structured thrice weekly on cognitive capacity, and related hormones like Leptin, Irisin, BDNF hormones, antioxidant status, and inflammatory cytokines, whether these modulations potentially enhance neuroprotection and mitigate age-related cognitive impairment among healthy adults.

Who can participate

Age range50 Years – 80 Years

SexALL

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Inclusion Criteria: * Sixty healthy individuals, aged 50 to 80 years (30 men/30 women), were invited to participate in this study after provided with informed consent and were included in this study. Also, all participants were of a sedentary lifestyle, with little or no physical activity during daily routine activities like work and transportation Exclusion Criteria: * To ensure accurate results, participants with obesity (BMI) ≥35 kg/m2.), physical impairments, movement limitations, chronic illnesses, such as kidney or liver diseases, or severe diabetes-related complications such as neuropathy, retinopathy, neuromuscular issues, cardiopulmonary conditions, or disorders affecting eating, the endocrine system, immune system, or mental health or those who undergoing glucocorticoid medication were excluded from this study

What they're measuring

Assessment of cognitive abilities

Timeframe: 6 months

2- Leisure-time physical activity (LTPA)

Timeframe: 6 months

3-Assessment of apoptotic-related proteins

Timeframe: 6 month

Trial details

NCT IDNCT07341568

SponsorKing Saud University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-10-30

View on ClinicalTrials.gov More Cognitive Impairment trials