Comparison of the Effects of N-acetylcysteine, Calcium Hydroxide, and Double Antibiotic Paste

Inclusion Criteria: * Non-vital teeth confirmed by clinical and pulp sensitivity tests * Teeth with a single canal and diagnosed with asymptomatic apical periodontitis * Periapical assessment (PAI) of 2 or greater * Teeth with a pocket depth not exceeding 3 mm * Teeth without excessive root curvature (Schneider class 1) and with visible root canals on radiographs * Permanent teeth with complete root development * Patients between the ages of 18 and 65 * Teeth without previous endodontic treatment Exclusion Criteria: * Patients who refused to participate in the study * Patients with any systemic disease * Patients who received antibiotic treatment within the last 3 months * Patients who were pregnant or suspected of being pregnant * Teeth with excessive crown damage that would not allow for the placement of a rubber dam * Teeth with root fractures, pathological findings or mobility, * Presence of any resorption in the involved tooth, * Patients with active swelling and tenderness to palpation.