The 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesth… (NCT07340255) | Clinical Trial Compass
RecruitingNot Applicable
The 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction
China60 participantsStarted 2025-09-29
Plain-language summary
Exploring the 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction: The aim is to determine the optimal ventilation pressure for esophageal insufflation avoidance during anesthesia induction and to explore its guiding significance for anesthesia management. The goal is to provide a more precise and personalized ventilation pressure setting standard for clinical anesthesia, thereby enhancing the safety of the anesthesia induction phase.
Who can participate
Age range18 Years – 65 Years
SexALL
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Inclusion criteria
✓. Age: 18-65 years, regardless of gender;
✓. ASA classification: I-III;
✓. Scheduled for elective general anesthesia surgery;
✓. Less than two from five criteria predicting difficult mask ventilation as described by Langeron et al.(Prediction of difficult mask ventilation. Anesthesiology 2000; 92:1229-36);
✓. No severe underlying conditions such as heart, lung, liver, or kidney disease;
✓. Signed informed consent and ability to cooperate with the study protocol.
Exclusion criteria
✕. Pregnant or breastfeeding women;
✕. History of upper gastrointestinal diseases such as gastroesophageal reflux disease, peptic ulcers, or hiatal hernia;
✕. Recent (within 2 weeks) respiratory infections, chronic cough, similar symptoms, and other known or predictable respiratory system diseases;
✕. Need for emergency surgery or airway obstruction after anesthesia induction requiring urgent intubation;
✕. Inability to achieve adequate oxygenation during mask ventilation (e.g., SpO₂ \< 92% for 30 seconds, unresponsive to treatment);