A Study of LY4064809 in Healthy Adult Participants (NCT07339735) | Clinical Trial Compass
CompletedPhase 1
A Study of LY4064809 in Healthy Adult Participants
United States24 participantsStarted 2026-01-12
Plain-language summary
The purpose of this study is to find out how much LY4064809 gets into the blood stream and how long it takes the body to get rid of it when it is given as two formulations. For each participant, the study will last about nine weeks. Participants will remain in the clinical research center for about one month.
Who can participate
Age range18 Years – 55 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Are healthy as determined by medical evaluation, including medical history, physical examination, vital signs, and electrocardiogram (ECG) at screening and admission.
* Have clinical laboratory test results within the normal range
* Have normal blood pressure and pulse rate or not clinically significant
* Have a BMI within the range 18 to 32 kg/m2
* Participants assigned male at birth or assigned female at birth who are not of childbearing potential
Exclusion Criteria:
* History or presence of any of the following conditions, deemed clinically significant by the investigator (or designee):
* metabolic disease, including congenital non-hemolytic hyperbilirubinemia, for example, Gilbert syndrome
* bile duct disease, including removal of the gall bladder
* digestive system disease
* blood disease
* disease of the nervous system
* significant history of, or presence of, liver disease, including any abnormal liver function tests
* heart disease
* Have an abnormal electrocardiogram (ECG) at screening or admission
* History of a major surgical procedure within 30 days prior to screening
* Diagnosed or treated cancer within 5 years prior to screening, with the exception of the following cancers cured through treatment: basal cell carcinoma of the skin, squamous cell carcinoma of the skin, and in situ carcinoma of the cervix cured through surgery
* Clinically significant history of multiple or severe drug hypersensitivity reactions or drug al…
What they're measuring
1
Pharmacokinetics (PK): Maximum Concentration (Cmax) of LY4064809
Timeframe: Predose on Day 1 Through Day 28
2
PK: Area Under the Concentration Versus Time Curve (AUC) of LY4064809