Double Stent for Biliary Stones in Cirrhotic Patients (NCT07337291) | Clinical Trial Compass
CompletedNot Applicable
Double Stent for Biliary Stones in Cirrhotic Patients
Egypt400 participantsStarted 2022-01-01
Plain-language summary
This prospective, single-center, interventional study enrolled 400 cirrhotic patients with large or complex common bile duct (CBD) stones that could not be removed during an initial Endoscopic Retrograde Cholangiopancreatography (ERCP). The study compared four different plastic biliary stenting strategies (single 10 Fr, double 10 Fr, single 11.5 Fr, and single 10 Fr pigtail stents) to determine the optimal approach for facilitating successful stone clearance in a subsequent ERCP and minimizing complications in this high-risk patient population.
Who can participate
Age range18 Years – 75 Years
SexALL
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Inclusion criteria
✓. Adults with established liver cirrhosis.
✓. Presence of large or complex common bile duct (CBD) stones that were non-retrievable during the initial ERCP.
✓. Classified as high-risk due to moderate to severe liver disease and/or substantial comorbidities, making them unable to safely tolerate extended endoscopic procedures or surgical intervention.
✓. Clinically stable and capable of undergoing the scheduled diagnostic and therapeutic procedures.
✓. Provided signed informed consent before enrollment.
Exclusion criteria
✕. Non-cirrhotic patients.
✕. Patients with non-calculous causes of biliary obstruction (e.g., portal biliopathy, benign biliary strictures, or malignant biliary obstruction).