An Exploratory Clinical Study on the Protective Effect of Cycling on the Ankle Joint in Gout (NCT07312396) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
An Exploratory Clinical Study on the Protective Effect of Cycling on the Ankle Joint in Gout
90 participantsStarted 2026-01-01
Plain-language summary
This study divided the enrolled gout patients into a jogging group and a cycling group to investigate 1)the effectiveness of cycling intervention in reducing the recurrence risk of gouty ankle arthritis compared with jogging. 2) To clarify the influence of different exercise patterns on the ultrasonic manifestations of gouty ankle arthritis; 3) Clarify the impact of different exercise methods on the blood uric acid levels of gout patients;
Who can participate
Age range18 Years – 60 Years
SexALL
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Inclusion Criteria:
* meets the diagnostic criteria for gout of the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) in 2015
* There have been two histories of gout attacks on either side of the ankle joint in the past six months
* Ultrasound examination within the past 6 months indicated that either ankle joint had characteristic ultrasound manifestations (double-track sign, and/or hyperechoic aggregates, and/or tophi, and/or bone destruction)
* Those who have had an interval of at least 4 weeks since the most recent acute gout attack
* If the patient is undergoing uric acid-lowering drug treatment, the drug dosage must remain stable for more than 4 weeks. During the study period, the uric acid-lowering drug regimen or dosage will not be adjusted
* For women who have the potential to become pregnant, a pregnancy test must be negative, they must not be in the lactation period, and it must be confirmed that they are receiving contraception approved by the researcher and agree to maintain this contraceptive measure throughout the study process
* Those who were informed of this study and signed the informed consent form
Exclusion Criteria:
* Those who have received intra-articular injections of corticosteroids during an attack within the past three months; Those who have taken colchicine, NSAIDs, glucocorticoids in the past two weeks, or those who need to maintain anti-inflammatory drug treatment for a long time during the follow-up pe…
What they're measuring
1
The frequency of gout attacks
Timeframe: From enrollment to the end of treatment at 24 weeks