The present study was a double-blind, randomised, controlled clinical trial with a parallel design, comparing the coronally advanced flap (CAF) with platelet-rich fibrin (PRF) and chorion membrane (CM) for the treatment of isolated gingival recession defects. A total of 50 patients were randomly divided into; Experimental site A: Twenty five sites were treated with coronally advanced flap (CAF) and platelet-rich fibrin (PRF) membrane; Experimental site B: Twenty five sites were treated with coronally advanced flap (CAF) and chorion membrane (CM)The study was conducted in accordance with the Declaration of Helsinki, protocol was developed and ethical clearance was obtained from the Institutional Ethics Committee, Institute of Dental Sciences, Bareilly, India \[IDS/ETHCC/14/08\]. As per protocol, a study was conducted in five phases: (1) initial screening; (2) initial therapy and clinical measurements; (3) surgical therapy; (4) maintenance phase; and (5) post-operative evaluation after 1 month, 3 months, and 6 months.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Recession depth (RD)
Timeframe: Baseline, prior to surgery and at 1 month, 3 months and 6 months follow-up visits
Recession width (RW)
Timeframe: Baseline, prior to surgery and at 1 month, 3 months and 6 months follow-up visits
Clinical attachment level (CAL)
Timeframe: Baseline, prior to surgery and at 1 month, 3 months and 6 months follow-up visits:
Width of keratinized gingiva (WKG)
Timeframe: Baseline, prior to surgery and at 1 month, 3 months and 6 months follow-up visits
Assessment of gingival biotype
Timeframe: Baseline, prior to surgery and at 1 month, 3 months and 6 months follow-up visits