The present study was a double-blind, randomised, controlled clinical trial with a parallel design, comparing the coronally advanced flap (CAF) with platelet-rich fibrin (PRF) and chorion membrane (CM) for the treatment of isolated gingival recession defects. A total of 50 patients were randomly divided into; Experimental site A: Twenty five sites were treated with coronally advanced flap (CAF) and platelet-rich fibrin (PRF) membrane; Experimental site B: Twenty five sites were treated with coronally advanced flap (CAF) and chorion membrane (CM)The study was conducted in accordance with the Declaration of Helsinki, protocol was developed and ethical clearance was obtained from the Institutional Ethics Committee, Institute of Dental Sciences, Bareilly, India \[IDS/ETHCC/14/08\]. As per protocol, a study was conducted in five phases: (1) initial screening; (2) initial therapy and clinical measurements; (3) surgical therapy; (4) maintenance phase; and (5) post-operative evaluation after 1 month, 3 months, and 6 months.
Age range
18 Years – 35 Years
Sex
ALL
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Recession depth (RD)
Timeframe: Baseline, prior to surgery and at 1 month, 3 months and 6 months follow-up visits
Recession width (RW)
Timeframe: Baseline, prior to surgery and at 1 month, 3 months and 6 months follow-up visits
Clinical attachment level (CAL)
Timeframe: Baseline, prior to surgery and at 1 month, 3 months and 6 months follow-up visits:
Width of keratinized gingiva (WKG)
Timeframe: Baseline, prior to surgery and at 1 month, 3 months and 6 months follow-up visits
Assessment of gingival biotype
Timeframe: Baseline, prior to surgery and at 1 month, 3 months and 6 months follow-up visits