CompletedNot Applicable

Effect of Tidal Volume on fURS Parameters

Turkey (Türkiye)70 participantsStarted 2025-09-01

Plain-language summary

The goal of this prospective clinical trial is to evaluate how intraoperative tidal volume settings affect surgical parameters and outcomes in adult patients undergoing flexible ureteroscopy (fURS) for kidney stones. The participant population includes patients over 18 years of age with unilateral, single renal stones located in the upper/middle calyx or renal pelvis. This study aims to answer are: Does intraoperative tidal volume influence operative time and surgical efficiency during fURS? Does tidal volume affect laser energy use, lasing efficiency, stone-free rates, and complication rates (infection or bleeding)? The investigators will compare two groups based on tidal volume recorded during anaesthesia: Group 1: Low tidal volume (\< 500 mL) Group 2: Standard tidal volume (≥ 500 mL) to determine whether tidal volume differences impact surgical performance and postoperative outcomes. Participants will: Undergo fURS performed under general anaesthesia with standard ASA monitoring, including ETCO₂ and TOF monitoring. Have their respiratory parameters (tidal volume, peak airway pressure, PEEP, respiratory rate, ETCO₂) and surgical data (operative time, laser settings, fluoroscopy use, stone-free status) recorded during and after surgery.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Age ≥18 years Unilateral, single kidney stones located in the upper or middle calyx or in the renal pelvis Exclusion Criteria: Chronic obstructive pulmonary disease (COPD) Pregnancy History of abdominal, retroperitoneal, or thoracic surgery Kidney anomalies Stones located in the lower calyx

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Correlation Between Intraoperative Respiratory Parameters and Surgical Outcomes

Timeframe: 2 months

Trial details

NCT IDNCT07304297

SponsorTarik Emre Sener

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-11-23

View on ClinicalTrials.gov More Urolithiasis trials