Human milk oligosaccharides (HMOs) represent the third largest solid component of breast milk. Technology advancements made it possible to supplement infant formulas with HMOs (2'FL, LNnT). Two published RCTs have demonstrated that infant formulas supplemented with 2'FL or 2'FL+LNnT are safe, well-tolerated, support normal grow, and may support healthy GI function and confer immune benefits. The performance of HMOs-supplemented formulas assessed in a real-world setting is complementary to previously conducted RCTs conducted in highly controlled clinical settings. Main objectives will be to document the growth and feeding tolerance of healthy term infants consuming an infant formula supplemented with HMOs in a real-world setting. In addition to it considering the potential health/immune benefits of HMOs, it is also important explore the incidences of illnesses (i.e., respiratory illnesses, GI illnesses, and fever) associated with consuming HMOs-supplemented formulas.
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World Health Organization (WHO) based weight-for-age z-scores Weight-for-age z-scores using WHO growth standards [Time Frame: 8 weeks (study end)]
Timeframe: 8 Weeks (Study End)
World Health Organization (WHO) based length-for-age z-scores
Timeframe: 8 Weeks (Study End)
World Health Organization (WHO) based weight-for-age z-scores
Timeframe: 8 Weeks (Study End)
World Health Organization (WHO) based weight-for-age z-scores
Timeframe: 8 Weeks (Study End)
World Health Organization (WHO) based weight-for-age z-scores
Timeframe: 8 Weeks (Study End)
Feeding Tolerance
Timeframe: 4 Weeks (Midpoint) and 8 Weeks (Study End Point)