Comparative Evaluation of Clinical and Radiographic Treatment Outcomes of Garlic Gel and Calcium Hydroxide as an Intracanal Medicament in Nonsurgical Root Canal Treatment of Permanent Teeth.

Inclusion Criteria: * Patients with the physical status of ASA I and ASA II according to ASA classification. * Patients aged from 15-45 years. * Mature permanent single-rooted teeth with closed apices. * Patients with clinical signs of symptomatic apical periodontitis (pain, tenderness to palpation, and percussion). * Patients having radiographic evidence of periapical radiolucency of endodontic origin. * Patients who have not taken antibiotics for the past 14 days. * Cooperative patients who show good compliance. Exclusion Criteria: * Patients with physical status of ASA III, IV, and V according to ASA classification. * Teeth with a calcified pulp chamber in periapical radiography. * Patients who have undergone previous endodontic treatment failure and those with the presence of sinus tract on clinical examination. * Teeth having advanced periodontal disease, with the basic periodontal examination (BPE) of 3 and 4. * Presence of internal and external resorption of the root as viewed on the periapical radiograph. * Presence of vertical root fracture and perforation as viewed on the periapical radiograph