CompletedNot Applicable

Sweet-Tasting Solution Versus Placebo to Reduce Pain During Local Anesthetic Injection in Children

Jordan54 participantsStarted 2026-01-01

Plain-language summary

The goal of this clinical trial is to learn whether applying a sugar-free flavored sweet solution (SFSS) before local anesthesia helps reduce injection pain in children. The main question it aims to answer is: Does SFSS reduce pain during dental local anesthesia compared to a placebo (plain water)? Researchers will compare the use of SFSS and a placebo to see which results in lower pain scores. Participants will: Receive SFSS or placebo before local anesthesia during two dental visits Have their pain measured using self-reported and observational pain scales Have their heart rate monitored during the procedure

Who can participate

Age range6 Years – 12 Years

SexALL

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Inclusion criteria

✓. Children who are 6-12 years of age.
✓. Children classified as ASA1 according to the American Society of Anesthesiologists.
✓. Children who have positive (Class III) or definitely positive (Class IV) behavior during preoperative behavioral assessments according to the Frankl Scale.
✓. Children who required bilateral local anesthesia infiltration injections on primary or permanent teeth either in the maxilla or mandible for dental treatment (different types of restoration, stainless steel crowns, pulp therapy, and extractions).
✓. Children with positive consent forms (signed and approved by their parents/ legal guardians) and attended the appointment.

Exclusion criteria

✕. Children who had a history of unpleasant experiences in dental settings.
✕. Children who had a history of unpleasant experience with local anesthesia injection.
✕. The presence of medically or developmentally compromising conditions.

What they're measuring

Self-reported pain using faces pain scale-revised (FPS-r)

Timeframe: Immediately after local anesthetic injection

Observer-reported pain using Revised Face, Legs, Activity, Cry, Consolability Scale

Timeframe: During administration of the local anesthetic injection

Physiological-Heart Rate

Timeframe: Baseline and During Injection

Trial details

NCT IDNCT07279285

SponsorUniversity of Jordan

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-04-01

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