Gabapentin and Diclofenac Sodium Comparison for Post-Operative Pain Relief (NCT07267182) | Clinical Trial Compass
CompletedNot Applicable
Gabapentin and Diclofenac Sodium Comparison for Post-Operative Pain Relief
Pakistan240 participantsStarted 2022-08-01
Plain-language summary
Little is known about comparative efficacy of gabapentin and diclofenac sodium in managing post-operative pain. Therefore, this study was planned to compare the efficacy of gabapentin, and diclofenac sodium for post-operative pain relief in patients undergoing major abdominal surgeries.
Who can participate
Age range18 Years – 60 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Any gender
* Aged 18-60 years
* Undergoing elective major abdominal surgery under general anesthesia
* With physical status I or II
* Who were able to comprehend and use the Visual Analogue Scale (VAS) for pain assessment
Exclusion Criteria:
* With a known allergy or contraindication to gabapentin, or diclofenac sodium
* A history of peptic ulcer disease
* A history of gastrointestinal bleeding
* Hepatic or renal dysfunction
* Pregnancy or lactation
* With neurological or psychiatric disorders affecting pain perception
* Received opioids, anticonvulsants, antidepressants, or nonsteroidal anti-inflammatory drugs (NSAIDs) within 24 hours before surgery
* With uncontrolled hypertension, ischemic heart disease, or diabetes mellitus
* Those who experienced intraoperative complications necessitating a change in anesthetic plan or postoperative mechanical ventilation