Effectiveness of Endorotor PED® System Versus Conventional Endoscopic Techniques for the Management of Walled-off Pancreatic Necrosis in Acute Necrotizing Pancreatitis: Randomized Single-blinded Controlled Superiority Trial and Cost-utility Analysis

Inclusion Criteria: * Age≥18years * ASA\<5 * CT scan less than 7 days old * Hospitalized for acute necrotizing pancreatitis, whatever the cause, and who have undergone drainage of pancreatic collections for the following indications according to the revised Atlanta criteria (infection, organ compression, persistent organ failure) * Have need for at least one DEN session despite endoscopic drainage (persistence of clinical symptoms or sepsis \>48h after drainage with collection still visible) Exclusion Criteria: * No endoscopic drainage in place for the management of WON * Have already had a DEN session (endoscopic or else) before screening for inclusion * Life-expectancy \< 1year (advanced cancer, etc) * Known haemostasis disorder (chronic thrombocytopenia, haemophilia, etc.) * Pregnant or breastfeeding woman * Subject deprived of freedom, subject under a legal protective measure * Non-affiliation to a social security regimen or CMU * Patient or person of confidence (if present at the time of inclusion) opposing the patient's participation in research * Subject already involved in another interventional clinical research