Researchers want to learn if using a study medicine called MK-1084 can help treat NSCLC. MK-1084 is a type of treatment called targeted therapy for the Kirsten rat sarcoma viral oncogene homolog (KRAS) G12C gene change. The goal of this study is to learn about the safety of MK-1084 and to learn how many people have the cancer get smaller or go away during the study treatment.
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Percentage of Participants with a Dose Limiting Toxicity (DLT)
Timeframe: Up to approximately 21 days
Percentage of Participants who Experience at Least One Adverse Event (AE)
Timeframe: Up to approximately 84 months
Percentage of Participants who Discontinue Study Intervention Due to an AE
Timeframe: Up to approximately 84 months
Objective Response Rate (ORR) per Response Evaluation Criteria In Solid Tumors (RECIST) 1.1 as assessed by Blinded Independent Central Review (BICR)
Timeframe: Up to approximately 84 months