CompletedPhase 4

EFFECT OF INTRAARTICULAR TRIAMCINOLONE HEXACETONIDE AND BETAMETHASONE ON INTRAOCULAR PRESSURE

Turkey (Türkiye)80 participantsStarted 2025-10-02

Plain-language summary

This study is being done to find out whether two commonly used corticosteroid injections for knee osteoarthritis - betamethasone and triamcinolone hexacetonide - have different effects on eye pressure (intraocular pressure). Adults with painful early-stage knee osteoarthritis who have not improved with standard treatments receive one of these injections into the knee joint as part of their usual care. Eye pressure in both eyes is measured before the injection and one week later. By comparing the change in eye pressure between the two steroid groups, the study aims to better understand the risk of steroid-related increases in eye pressure and to help doctors choose safer treatment options, especially for patients who may be at risk for glaucom

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Symptomatic early-stage knee osteoarthritis Patients aged 18-75 years No prior eye surgery No history of elevated IOP or glaucoma diagnosis Patients not receiving any medical treatment altering IOP Exclusion Criteria: * IOP \>21 mm Hg Patients with a previous or current diagnosis of glaucoma Patients aged \<18 and \>75 years History of or ongoing ocular disease Use of medications (oral CSs, diazoxide, etc.) altering IOP

What they're measuring

Change in Intraocular Pressure (IOP) From Baseline to 1 Week

Timeframe: Baseline (before intra-articular steroid injection) and 1 week after injection

Trial details

NCT IDNCT07242846

SponsorNigde Omer Halisdemir University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-11-02

View on ClinicalTrials.gov More Knee Osteoarthritis (Knee OA) trials