CompletedNot Applicable

SurgiPerito Trial: High-Purity Type-I Collagen for Peritoneal Reconstruction After Cytoreductive Surgery

India60 participantsStarted 2025-10-20

Plain-language summary

This dual-centre, randomized controlled trial evaluates the safety and efficacy of high-purity Type-I collagen-based biomaterial, as a peritoneal substitute following peritonectomy in patients undergoing cytoreductive surgery (CRS) for peritoneal surface malignancy. The study tests whether Surgicoll-Mesh can reduce major postoperative intra-abdominal complications compared with standard management.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥18 years * Diagnosed peritoneal surface malignancy (colorectal, ovarian, appendiceal, mesothelioma, pseudomyxoma) * Undergoing cytoreductive surgery ± HIPEC requiring peritonectomy * ECOG 0-2, adequate organ function, informed consent Exclusion Criteria: * Collagen allergy or active infection * Immunosuppression or chronic steroid use * Pregnancy/lactation * Uncontrolled sepsis, bowel perforation, or extensive small bowel resection

What they're measuring

Incidence of Major Intra-abdominal Complications

Timeframe: 2 months post-surgery

Trial details

NCT IDNCT07241091

SponsorAdichunchanagiri Institute of Medical Sciences, B G Nagara

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-02-13

Results submitted2026-03-07

View on ClinicalTrials.gov More Peritoneal Surface Malignancy trials