CompletedNot Applicable

The Relationship Between Central Sensitization, Pain, and Psychosocial Factors in Individuals With Lipedema

Turkey (Türkiye)60 participantsStarted 2025-10-10

Plain-language summary

This cross-sectional study will include women aged 18-75 with clinically diagnosed lipedema and healthy controls. Sociodemographic and clinical data will be collected, and participants will complete the Central Sensitization Inventory (CSI), Visual Analog Scale (VAS), Hospital Anxiety and Depression Scale (HADS), and Pain Catastrophizing Scale (PCS). Pain pressure thresholds (PPT) will be assessed using a digital algometer at the middle deltoid, lateral thigh, and medial knee, with three measurements taken at each site and the average recorded.

Who can participate

Age range18 Years – 75 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Clinically diagnosed with lipedema * Aged between 18 and 75 years * Provided voluntary informed consent Exclusion Criteria: * History of systemic diseases such as diabetes, rheumatologic disorders, or malignancy * Presence of neurological disorders (e.g., polyneuropathy, multiple sclerosis, history of stroke) * Currently under active psychiatric treatment Pregnancy * History of lower extremity surgery or major trauma within the past 6 months * Received injection therapy or physical therapy for the lower extremities within the past 6 -months * History of infection or active dermatological disease affecting the lower extremities

What they're measuring

Central Sensitization Inventory (CSI)

Timeframe: Baseline

Trial details

NCT IDNCT07240285

SponsorIstanbul Physical Medicine Rehabilitation Training and Research Hospital

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2025-11-10

View on ClinicalTrials.gov More Lipedema trials