This single-center, randomized, open-label study will assess the relative bioavailability of 2 miricorilant (CORT118335) tablet formulations.
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Time of Maximum Observed Concentration (Tmax) of Miricorilant
Timeframe: Predose and at serial timepoints up to 72 hours postdose
Maximum Observed Concentration (Cmax) of Miricorilant
Timeframe: Predose and at serial timepoints up to 72 hours postdose
Concentration at 24 Hours Postdose (C24) of Miricorilant
Timeframe: Predose and at serial timepoints up to 24 hours postdose
Area Under the Curve from Time 0 to the Time of Last Measurable Concentration (AUC[0-last]) of Miricorilant
Timeframe: Predose and at serial timepoints up to 72 hours postdose
Area Under the Curve from Time 0 Extrapolated to Infinity (AUC[0-inf]) of Miricorilant
Timeframe: Predose and at serial timepoints up to 72 hours postdose
Terminal Elimination Half-Life (T1/2) of Miricorilant
Timeframe: Predose and at serial timepoints up to 72 hours postdose
Relative Bioavailability (Frel) for Miricorilant Based on Cmax
Timeframe: Predose and at serial timepoints up to 72 hours postdose
Frel for Miricorilant based on AUC(0-last)
Timeframe: Predose and at serial timepoints up to 72 hours postdose
Frel for Miricorilant Based on AUC(0-inf)
Timeframe: Predose and at serial timepoints up to 72 hours postdose