This multicenter, cluster-randomized, cluster-crossover clinical trial evaluates the impact of three intraoperative FiO2 (Fraction of Inspired Oxygen) oxygenation strategies-lower (FiOâ‚‚ 0.21-0.40), intermediate (FiOâ‚‚ 0.40-0.80), and higher (FiOâ‚‚ 0.80-1.00)-on postoperative organ injury and mortality in adult surgical patients. The trial aims to determine the optimal oxygenation strategy to improve perioperative outcomes.
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Composite of organ injury or in-hospital death within 30 days of surgery
Timeframe: 30 days post-surgery