Active — Not RecruitingNot Applicable

HABIT-ILE + FST in Children With SMA

United States5 participantsStarted 2025-10-01

Plain-language summary

This single-arm pilot study will assess the feasibility and preliminary effectiveness of an intensive motor skill intervention (HABIT-ILE) combined with functional strength training (FST) in children with SMA who are receiving disease-modifying therapies. Participants will attend one 6-hour HABIT-ILE + FST session each weekend (Saturday or Sunday) for 15 weeks, for a total of 90 hours of training. Feasibility will be evaluated through questionnaires, and effectiveness through standardized motor function assessments.

Who can participate

Age range5 Years – 17 Years

SexALL

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Inclusion Criteria: * Diagnosis of SMA * Able to participate in all pre and post intervention assessments * Able to understand and speak English * Able to understand directions (no significant cognitive delay or serious behavioral issues that would limit participation) * Receiving a stable dose of disease-modifying therapies for at least 6 months prior to enrollment. Exclusion Criteria: * Orthopedic surgery within the last year (confound) * Initiation of any new pharmaceutical treatment during the study period * Participation in a clinical trial of an investigational therapy

What they're measuring

Feasibility questionnaire

Timeframe: Immediately after the intervention

Trial details

NCT IDNCT07223320

SponsorTeachers College, Columbia University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-31

View on ClinicalTrials.gov More SMA - Spinal Muscular Atrophy trials