A Clinical Study Conducted in the Bangkok, Thailand Area, to Investigate the Clinical Efficacy of… (NCT07223073) | Clinical Trial Compass
CompletedPhase 3
A Clinical Study Conducted in the Bangkok, Thailand Area, to Investigate the Clinical Efficacy of a New Toothpaste
Thailand80 participantsStarted 2017-12-21
Plain-language summary
To investigate the clinical efficacy of a new toothpaste containing 0.454% stannous fluoride as compared to a regular fluoride toothpaste containing 0.76% sodium monofluorophosphate on oral malodor reduction via organoleptic scores 12 hours post-brushing overnight after 3 weeks of twice a day (morning and evening) product use.
Who can participate
Age range18 Years – 70 Years
SexALL
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Inclusion Criteria:
* Male and female adults between the ages of 18-70 (inclusive)
* Subjects must be in general good health
* Subjects must be in good oral health based on self-assessment
* Subjects must be available for the duration of the study for all time point assessments
* Subjects were required to possess a minimum of 20 natural uncrowned teeth (excluding third molars)
* Subjects were required to sign an Informed Consent form
* No known history or allergies to personal care/consumer products or their ingredients.
Exclusion Criteria:
* Participated in any other oral clinical studies during the duration of this study
* Had full or partial (upper or lower) dentures
* Women who are pregnant or lactating (breast feeding)
* Use of tobacco products, (5) History of allergies to common mouthwash ingredients
* Use of phenolic flavored products, such as mint flavored candies and chewing gum the morning of the study of during the sampling periods
* Immune compromised individuals (HIV, AIDS, immune suppressive drug therapy
* Individuals who, due to medical conditions cannot go without eating or drinking for the post use treatment evaluation time points (6-hours plus overnight).
What they're measuring
1
Mean Organoleptic scores for each treatment group
Timeframe: Baseline, 12 hours post brushing and 3 weeks