The purpose of this study is to evaluate the pharmacokinetics, safety, and efficacy of povorcitinib in adolescent participants with moderate to severe hidradenitis suppurativa over a 54-week open-label treatment period.
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Proportion of participants with Treatment-Emergent Adverse Events (TEAEs)
Timeframe: Baseline through Week 54
Apparent clearance
Timeframe: Up to Week 24
Apparent volume of distribution
Timeframe: Up to Week 24
Apparent oral absorption rate constant
Timeframe: Up to Week 24
Absorption lag time
Timeframe: Up to Week 24
Maximum plasma drug concentration at steady state
Timeframe: Up to Week 24
Average plasma drug concentration at steady state
Timeframe: Up to Week 24
Plasma concentration at steady state for the dosing interval
Timeframe: Up to Week 24
Time to maximum plasma concentration at steady state
Timeframe: Up to Week 24
Terminal half-life
Timeframe: Up to Week 24