Patient-Reported Symptom Care Versus Usual Care After Esophageal Cancer Surgery: A Single-Center … (NCT07211009) | Clinical Trial Compass
Not Yet RecruitingPhase 3
Patient-Reported Symptom Care Versus Usual Care After Esophageal Cancer Surgery: A Single-Center Phase 3 Randomized Trial
240 participantsStarted 2025-10-15
Plain-language summary
Symptom management is fundamental to clinical care, and symptom monitoring is an effective means to detect potential adverse events early and prevent serious complications. Extensive studies show that symptom management based on patient-reported outcomes (PROs) can reduce symptom burden, improve functional status and quality of life, lower emergency visits and readmissions, and even prolong survival. However, in the field of esophageal cancer surgery, prospective clinical studies assessing the feasibility of postoperative PRO-based symptom management remain lacking. This project proposes a randomized controlled trial (RCT) in China to systematically evaluate the effectiveness and feasibility of PRO-based symptom management after esophageal cancer surgery. Through this clinical study, we aim to assess both the impact and the implementability of introducing a proactive, patient-centered PRO symptom-management model into esophageal surgical care.
Who can participate
Age range18 Years – 75 Years
SexALL
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Inclusion criteria
✓. Age 18-75 years.
✓. Pathologically confirmed esophageal cancer.
✓. Planned to undergo curative (radical) surgical resection.
✓. R0 resection.
✓. Eastern Cooperative Oncology Group (ECOG) performance status (PS) ≤ 1.
✓. Adequate function of major organs.
✓. Willing to complete questionnaire surveys.
✓. Voluntarily agrees to participate and signs the informed consent form.
Exclusion criteria
✕. Human immunodeficiency virus (HIV) infection.
✕. Psychiatric disorder.
✕. Any other malignancy within the past 5 years (except completely cured carcinoma in situ of the cervix or basal cell/squamous cell carcinoma of the skin).
What they're measuring
1
90-Day Postoperative Complication Rate After Esophagectomy
Timeframe: Postoperative days 7, 14, 30, 60, and 90, complications will be assessed and recorded at each time point.