CompletedNot Applicable

Economic Evaluation of Mindline.sg

Singapore242 participantsStarted 2025-11-20

Plain-language summary

This study aims to evaluate the effectiveness of mindline.sg, a digital mental health platform, in improving mental health literacy, emotional wellbeing, quality of life, and economic outcomes among adults in Singapore. We will conduct a randomized controlled trial (RCT) with two phases: an initial screening and a 1-month intervention. Eligible participants, identified based on mental health symptom scores, will be randomly assigned to either an intervention group using mindline.sg or a control group receiving standard mental health information. The intervention group will receive weekly prompts to engage with key features of the platform, including psychoeducation, positive psychology tools, emotion regulation exercises, and access to digital navigation for mental health services. Participants in both groups will complete surveys at baseline, post-intervention, and two months post-intervention, measuring outcomes such as mental health symptoms, resilience, wellbeing, emotion regulation, mental health literacy, and work performance. We expect mindline.sg users to show greater improvements across mental health and quality of life indicators, increased mental health literacy, and better work productivity compared to controls. This study will provide evidence on the utility of digital mental health tools in supporting population mental wellbeing and inform future digital mental health strategies in Singapore and similar contexts.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged at least 21 years or at least 18 years old if National of University student * Have lived in Singapore for at least 2 years * Have not received a formal diagnosis of a psychiatric disorder * Not currently receiving any form of mental health treatment (e.g., counselling) * Fluent in English * Participants from screening whose DASS-21 scores are mild or moderate for any one of the sub scales. Exclusion Criteria: \- Those who do not meet the inclusion criteria will be screened and excluded.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Mental health symptoms by 21-item Depression, Anxiety and Stress Scale (DASS-21)

Timeframe: Screening, baseline, 4 weeks after baseline, 12 weeks after baseline

Quality of Life by 6-item EQ-5D-5L scale

Timeframe: Baseline, 4 weeks after baseline, 12 weeks after baseline

Work productivity by WHO-HPQ measure of absenteeism and presenteeism

Timeframe: 4 weeks after baseline, 12 weeks after baseline

Trial details

NCT IDNCT07209904

SponsorCentre for Evidence and Implementation Singapore Ltd

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-05-30

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