EIT-guided PEEP Titration Versus Standard Ventilation in Bariatric Surgery (NCT07207772) | Clinical Trial Compass
RecruitingNot Applicable
EIT-guided PEEP Titration Versus Standard Ventilation in Bariatric Surgery
China118 participantsStarted 2025-07-28
Plain-language summary
This study is a prospective, single-center, single-blind, randomized controlled clinical trial. Patients scheduled for laparoscopic bariatric surgery will be selected and randomly assigned to either the EIT-guided individualized PEEP group (Group P-eit) or the control group (Group P-8). Group P will be ventilated using the PEEP value determined by EIT, while Group C will be ventilated with a fixed PEEP value of 8 cmH2O.The primary outcome is the incidence of postoperative pulmonary complications (PPCs) within 72 hours after surgery.
Who can participate
Age range18 Years – 65 Years
SexALL
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Inclusion criteria
✓. Age between 18 and 65 years;
✓. Plan to receive laparoscopic bariatric surgery under general anesthesia;
✓. American Society of Anaesthesiologists (ASA) physical status I-III;
✓. BMI between 30 and 55 kg/m2;
✓. Voluntary participation in this study and signing of an informed consent form.
Exclusion criteria
✕. History of smoking or previous thoracic surgery;
✕. Invasive mechanical ventilation within 30 days;
✕. Pregnancy;
✕. Allergy to EIT electrodes;
✕. Persistent hemodynamic instability or refractory shock;
✕. Severe cardiopulmonary disease (e.g., severe COPD (Chronic obstructive pulmonary disease), NYHA (New York Heart Association) Class III or IV, acute coronary syndrome, or sustained ventricular tachycardia);
What they're measuring
1
incidence of postoperative pulmonary complications