RecruitingNot Applicable

A Randomized Controlled Trial Comparing Whole Body Vibration Therapy With Usual Care and Usual Care to Improve Muscle Health in Older Adults

Singapore40 participantsStarted 2026-01-10

Plain-language summary

This study is a randomized controlled trial where participants would be randomly assigned to one of 2 groups. One group would receive Whole body vibration therapy and usual care and the other group only usual care. Measurements of muscle mass, strength and function would be taken before the interventions, and at 2 other points after interventions. Differences in the outcomes between the two groups would be analysed.

Who can participate

Age range

65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy Volunteer or Patients aged 65 and above, * Clinical frailty Scale (CFS) score of 3-4, * Independently ambulating without any aid * willingness and consent to participate in the study and ability to travel to the study-site for the measurements and interventions, and * participants with no regular exercise habits (defined as less than 150mins/week of moderate intensity aerobic exercise and less than twice a week of strengthening exercises)for past 3 months. Exclusion Criteria: * current active enrolment into any Day Rehab or community exercise program, * contraindications to WBVT machine usage (see below), * diagnosis of dementia, * history of Diabetes Mellitus * BMI ≤20kg/m2, * recent hospital admissions within the last 3 months, * end stage organ failure, * chronic diseases which are not well managed, for example, poorly controlled hypertension, * New York Heart Association (NYHA) score II and above for patients with history of heart failure and * MUST Score ≥1. Contraindications to WBVT: PRIMARY CONTRAINDICATIONS TO WBVT * Pregnancy * Acute thrombosis (acute vascular occlusion) * Artificial joints in stimulated body regions * Fresh fractures in stimulated body regions * Within 3 months post surgery/procedure and/or any fresh wounds and scars in the stimulated body regions * or if the wound healing is not yet completely finished. SECONDARY CONTRAINDICATIONS TO WBVT * Acute inflammation of the musculoskeletal system, activated arthrosis o…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Isometric Knee Extension Strength

Timeframe: Baseline and 2 weeks after intervention and 3 months after intervention

Trial details

NCT IDNCT07205133

SponsorChangi General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-03-31

Contact for this trial

Christine Yuanxin Chen, MBBS

+65-9030 4976 christine.chen.y.x@singhealth.com.sg

View on ClinicalTrials.gov More Aging trials