Active — Not RecruitingPhase 1

Chewing Gum vs. Ondansetron as Rescue Treatment for PONV in Female Patients

Lebanon90 participantsStarted 2025-08-22

Plain-language summary

The proposed randomized clinical trial aims to test and compare the efficacy of chewing gum vs. Intravenous antiemetic ondansetron as rescue treatment for post-operative nausea and vomiting (PONV) among Lebanese female patients undergoing laparoscopic surgery in the post-operative anesthesia care unit (PACU).

Who can participate

Age range18 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Females * Aged 18 and above, * Weight 40kg and above, * Who have undergone laparoscopic * Surgery under volatile anesthetic-based general anesthesia. Exclusion Criteria: * Have history of motion sickness, * Maintained anesthesia during surgery using Propofol-pump * Were given antiemetics within 8 hours pre-surgery * Allergy to ondansetron * Planned mechanical ventilation post-operation

What they're measuring

Complete cessation of PONV with no recurrence and no rescue medication

Timeframe: 2 hours

Trial details

NCT IDNCT07201883

SponsorMakassed General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-02-28

View on ClinicalTrials.gov More Postoperative Nausea and Vomiting (PONV) trials