Study of the Efficacy of Dietary Supplementation in Targeting Sleep Quality (NutriSom-01B) (NCT07200167) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Study of the Efficacy of Dietary Supplementation in Targeting Sleep Quality (NutriSom-01B)
Slovenia70 participantsStarted 2025-10-01
Plain-language summary
single-center, randomized, cross over, double-blind, placebo controlled intervention study
Who can participate
Age range24 Years – 65 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria:
* subject Informed consent form (ICF) is signed
* aged 24-65 years at the time of the signature of ICF
* suboptimal sleep quality according to Pittsburgh Sleep Quality Index (PSQI-SI): PSQI \> 5
* no clinically significant (subthreshold) insomnia according to Pittsburgh Sleep Quality Index (PSQI-SI) (Kmetec et al., 2022): PSQI \<= 9
* a body mass index (BMI) \<= 32 kg/m2
* stable medications for non excluded concurrent medical conditions for six weeks prior to the screening visit
* ability to ingest oral food supplement (study product)
* willing to follow all study procedures, including attending all site visits and use of actigraphy
Exclusion criteria:
* diagnosed or subject to therapy due to sleep disorders
* acute infectious disease
* any kind of chronic pharmacological therapy with antihypertensives or antidepressants
* any kind of other pharmacological therapy that could interact with active ingredients used in the study
* pregnancy or planned pregnancy, lactation, menopause (with pharmacological treatment)
* use of beta-blockers
* chronic use of use of prostaglandin synthesis inhibitors (nonsteroidal anti-inflammatory drugs), such as acetylsalicylic acid and ibuprofen
* supplementation with melatonin or other food supplements intendent for sleep quality during last 2 weeks
* unwillingness to maintain caffeine abstinence after 4:00 PM during the study
* not having a mobile upper extremity for attaching an actigraph
* known alcohol and/or drug abuse…
What they're measuring
1
Difference in sleep onset latency (SOL) compared to placebo