Prospective, observational (consecutive eligible eyes) continuation of a previously published 6-month cohort from the same center, extending follow-up to 12 months. Patients with progressive keratoconus received either conventional (CXL30: 3 mW/cm² × 30 min) or accelerated (CXL10: 9 mW/cm² × 10 min) epi-off CXL as part of routine clinical care. Assignment to CXL30 or CXL10 was at the discretion of the treating surgeon; no prospective allocation or randomization was performed. Outcomes included ABCD grading metrics (ABCD-A/B), Kmax, anterior/posterior radii of curvature (ARC/PRC), thinnest pachymetry, and visual acuity at 12 months. The primary objective was to evaluate one-year stabilization/remodeling and compare anterior/posterior responses between protocols.
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Change in ABCD-A from baseline to 12 months
Timeframe: 12 months