Microflow3D - Non-invasive Mapping of Coronary Arteries and the Cerebral Vascular Network Using 3… (NCT07193225) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Microflow3D - Non-invasive Mapping of Coronary Arteries and the Cerebral Vascular Network Using 3D Ultrasound Localization Microscopy in Patients With Atherosclerosis Prior to Carotid Endarterectomy Surgery
France37 participantsStarted 2025-11-01
Plain-language summary
There is a need to simplify the assessment of coronary and cerebral vascular networks in patients selected for carotid endarterectomy in order to prevent potential complications during and after surgery. A non-invasive, non-ionizing 3 dimension mapping of these networks would provide a remarkable benefit for patients.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Patients with asymptomatic carotid stenosis, without recent stroke, and scheduled for carotid endarterectomy within the next 30 days.
* Age ≥ 18 years.
* Beneficiary of a social security system or equivalent coverage.
* Signed informed consent.
* Patients already enrolled in another biomedical research study may also participate in this study.
Exclusion Criteria:
* Contraindication to the use of the ultrasound contrast agent SonoVue®: known hypersensitivity to the active substance or to any of the following excipients: Macrogol 4000; Distearoylphosphatidylcholine; Sodium dipalmitoylphosphatidylglycerol; Palmitic acid.
* Allergy to ultrasound gel.
* Refusal or inability (linguistic or psychological) to sign the informed consent form.
* Subject to legal protection measures, such as guardianship (in accordance with Article L1122-2 of the French Public Health Code).
* Pregnant or breastfeeding women cannot participate in this study.
What they're measuring
1
Detecting the presence of an incomplete circle of Willis