A Study to Evaluate the Safety and Effectiveness of JUVÉDERM Products in Adult Participants for t… (NCT07186595) | Clinical Trial Compass
Active — Not RecruitingPhase 4
A Study to Evaluate the Safety and Effectiveness of JUVÉDERM Products in Adult Participants for the Change of Their Overall Facial Appearance
United States75 participantsStarted 2025-09-25
Plain-language summary
The purpose of this study is to evaluate the safety and effectiveness of JUVÉDERM products in adults seeking improvement in facial volume and/or skin quality.
Who can participate
Age range22 Years – 65 Years
SexALL
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Inclusion Criteria:
* Must meet at least 3 of the following criteria for treatment in the face with at least 2 JUVÉDERM products, per investigator's assessment:
* Minimal, moderate, or severe on Allergan Temple Hollowing Scale (ATHS)
* Moderate or severe for both eyes on Allergan Infraorbital Hollow Scale (AIHS)
* Moderate or severe on Allergan Cheek Smoothness Scale (ACSS)
* Moderate, significant, or severe on Mid-face Volume Deficit Scale (MFVDS)
* Moderate or severe on Nasolabial Fold Severity Scale (NLFSS)
* Minimal, mild, or moderate on Allergan Lip Fullness Scale 2 (ALFS2)
* Moderate or severe on Allergan Chin Retrusion Scale (ACRS)
* Moderate or severe on Allergan Loss of Jawline Definition Scale (ALJDS)
* Must be in good health as determined by subject's medical history, physical examination, and vital sign measurements.
Exclusion Criteria:
* Prior treatment with non-permanent soft tissue fillers or fat-reducing injectables in the face or neck within 12 months prior to screening.
* Excessively loose skin in the face and/or neck.
* Tendency to develop hypertrophic scarring and/or keloid scarring.
What they're measuring
1
Change from Baseline in the Participant's Rasch-Transformed Score of the FACE-Q™ Satisfaction with Facial Appearance Scale