Comparing Artificial Intelligence and Physicians: A Vignette-Based Study in Pediatric Clinical De… (NCT07179861) | Clinical Trial Compass
CompletedNot Applicable
Comparing Artificial Intelligence and Physicians: A Vignette-Based Study in Pediatric Clinical Decision-Making
Turkey (Türkiye)30 participantsStarted 2025-08-27
Plain-language summary
This study evaluates how well anonymized artificial-intelligence (AI) tools perform on standardized pediatric case vignettes and whether showing AI suggestions can improve clinicians' answers. About 30 board-certified/eligible pediatric specialists at a single hospital complete a one-time session. Participants are randomized to two groups. Group A (n≈15): physicians answer each vignette once. Group B (n≈15): physicians answer and rate confidence (1-10), then review anonymized suggestions from five different AI tools (tool names not shown) and may keep or change their answer; changes and confidence are recorded.
Primary focus: measure AI performance (diagnostic accuracy, medication-dosing accuracy, interpretation accuracy) overall and by difficulty tier, and record AI response time. Secondary focus: quantify how AI suggestions affect human performance (change in accuracy, direction of change, confidence shift, and time). No patients or biospecimens are involved; risks are minimal (time and possible discomfort with performance review). Findings may inform safe, evidence-based ways to use AI alongside clinicians in pediatrics.
Who can participate
Age range
28 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Board-certified or board-eligible pediatric specialist (general pediatrics) (in the first 10 years of expertise)
* Actively practicing at the participating institution/network at the time of enrollment.
* Able and willing to complete all vignette items individually in a single session and to follow study instructions for the assigned cohort (direct answers or confidence rating + viewing anonymized AI suggestions).
* Fluent in Turkish and able to use a computer interface.
* Provides written informed consent.
Exclusion Criteria:
* Pediatric subspecialist practice as primary role (e.g., cardiology, infectious diseases, neurology, neonatology, etc.), to maintain a homogeneous general pediatrics cohort.
* Prior access to or participation in creating the study vignettes, answer keys, or scoring rubrics; direct involvement with the study team.
* Inability to complete the session without external help or use of non-protocol resources (internet/AI tools) during answering (outside of anonymized AI suggestions shown by the system in Group 2).
* Failure to complete ≥90% of items or major protocol deviation (e.g., discussion with others during the task).
* Any condition judged by investigators to interfere with valid participation (e.g., severe time constraints, inability to provide consent).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.