CompletedNot Applicable

Effect of Inspiratory Muscle Training on Diaphragm and Ab-dominal Wall Muscle Thickness With Fatty Liver Density in Elderly Women: A Randomized Controlled Trial

Turkey (Türkiye)26 participantsStarted 2025-06-05

Plain-language summary

Background: Post-menopausal estrogen decline is considered a contributing factor to sarcopenia, and inspiratory muscle training (IMT) may provide benefits in this demo-graphic. This study examined the impact of a four-week IMT program on diaphragm thickness, abdominal wall muscle thickness (AWMT; transversus abdominis, internal oblique, and external oblique), and liver fat percentage in healthy elderly women. Methods: Twenty-six women aged 60-80 years were randomly assigned to an IMT group (n = 13) or a control group (n = 13). The IMT group used the PowerBreathe® Classic device at 40% of maximal inspiratory pressure (MIP), with weekly increments of 10%. Training was performed twice daily, five days per week, with 30 breathing cycles per session (60 per day). The control group maintained their usual routines. AWMT, diaphragm thickness (DT), and fatty liver density (FLD) were measured by a radiologist before and after the intervention.

Who can participate

Age range60 Years – 80 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * were defined as women aged 60-80 years (post-menopausal), who were independent in activities of daily living, * demonstrated adequate cognitive function to follow instructions, * had no musculoskeletal injury within the previous six months, * were non-smokers, * had routine thoracic or abdominal CT images obtained for clinical indications and used in this study. Exclusion Criteria: * included having uncontrolled cardiovascular or pulmonary disease such as heart failure or COPD/asthma exacerbation, * uncontrolled hypertension, diagnosed chronic liver disease, * acute respiratory infection within the last four weeks, * participation in structured respiratory or resistance training within the last six months, * recent thoracoabdominal surgery or hernia, use of medications known to affect muscle or liver metabolism such as systemic corticosteroids, anabolic agents, or hepatotoxic drugs, * severe orthopedic or neurological conditions limiting mobility, or refusal to participate.

What they're measuring

pre-training

Timeframe: 4 week

pre-training

Timeframe: 4 Week

pre-training

Timeframe: 4 week

Trial details

NCT IDNCT07168733

SponsorGümüşhane Universıty

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-07-15

View on ClinicalTrials.gov More Perceived Recovery trials

Plain-language summary

Who can participate

Age range60 Years – 80 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.