RecruitingNot Applicable

Do Increasing Preoperative Timing of Single Dexmedetomidine Dose Have an Effect on Stress Response of Laryngoscopy and Intubation?

Egypt45 participantsStarted 2025-09-11

Plain-language summary

This study aims to evaluate the effect of increasing preoperative timing of single dexmedetomidine on the stress response of laryngoscopy and intubation.

Who can participate

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age from 18 to 65 years. * Both sexes. * American Society of Anesthesiology (ASA) physical status I-II. Exclusion Criteria: * Severe cardiovascular problems. * Respiratory disorders. * Diabetes. * Hypertension. * Obesity. * Allergic reaction to study drugs. * Patients on antihypertensive medication (α-methyldopa, clonidine, or other α2-adrenergic agonists) * Medications that affect heart rate (HR) or blood pressure (BP). * Pregnant. * Currently breast-feeding women. * History of sleep apnea. * Those for emergency procedures.

What they're measuring

Mean arterial pressure

Timeframe: Till the end of the surgery (Up to 2 hours)

Trial details

NCT IDNCT07165483

SponsorTanta University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-03-01

Contact for this trial

Mohammed S Elsharkawy, MD

00201148207870 mselsharkawy@med.tanta.edu.eg

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