Evaluating the Effect of N-Acetyl Cysteine and Alpha Lipoic Acid in Patients With Beta Thalassemia

Inclusion Criteria: * Patients with beta-thalassemia who will receive conventional thalassemia management. * Both genders. * Age ≥ 18 years old. Exclusion Criteria: * Patients with familial hypercholesterolemia or history of premature atherosclerosis. * Patients with a prior history of significant cardiovascular diseases, such as coronary artery disease, myocardial infarction, or stroke. * Patients with severe renal dysfunction. * Patients with severe hepatic dysfunction. * Patients with diabetes. * Patients who will be non-compliant with the prescribed therapy. * Patients with other hemoglobinopathies. * Pregnant women. * Obese patients. * Patients who will receive antioxidant or anti-inflammatory medications. * Patients with inflammatory diseases, such as Systemic lupus erythematous, rheumatoid arthritis and inflammatory bowel disease. * Patients with oxidative stress related diseases, such as Alzheimer, Parkinson, COPD and cancer.