This prospective, randomized controlled study evaluates the hemodynamic effects of prone and supine positions during percutaneous nephrolithotomy (PNL) for large kidney stones. Surgical position may influence intraoperative and postoperative hemodynamic stability. Prone positioning can increase intrathoracic pressure and reduce venous return, whereas supine positioning may provide greater hemodynamic stability. A total of 84 patients will be randomized to undergo PNL in prone or supine positions. Primary outcomes include changes in hemodynamic parameters during surgery. Results may guide surgical position selection, especially in patients with potential hemodynamic risk.
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Change in Hemodynamic Parameters (Intraoperative)
Timeframe: From induction of anesthesia to the end of surgery (approximately 60-120 minutes)
Change in Arterial Blood pH
Timeframe: Preoperative, intraoperative, postoperative day 1
Change in Diastolic Blood Pressure (Intraoperative)
Timeframe: From induction of anesthesia to the end of surgery (approximately 60-120 minutes
Change in Mean Arterial Pressure (Intraoperative)
Timeframe: From induction of anesthesia to the end of surgery (approximately 60-120 minutes)
Change in Heart Rate (Intraoperative)
Timeframe: From induction of anesthesia to the end of surgery (approximately 60-120 minutes)
Change in Arterial pOâ‚‚
Timeframe: Preoperative, intraoperative, postoperative day 1
Change in Arterial HCO₃-
Timeframe: Preoperative, intraoperative, postoperative day 1
ARİF BURAK KEÇEBAŞ, UROLOGY CLINIC DOCTOR
Change in Oxygen Saturation
Timeframe: Preoperative, intraoperative, postoperative day 1
Change in Arterial pCOâ‚‚
Timeframe: Preoperative, intraoperative, postoperative day 1