CompletedNot Applicable

Study of Efficacy and Safety of Cream Infused With HuangQin (Root of Scutellaria Baicalensis) Extract for the Reduction of Hyperpigmentation

Thailand38 participantsStarted 2025-04-01

Plain-language summary

The aim of this study is to evaluate the efficacy of a topical cream infused with Scutellaria baicalensis extract in reducing hyperpigmentation on the face. The study is experimental clinical pilot study as a single group pretest-posttest. A ROAT is conducted 1 week prior to the experiment. Participant apply the cream on the hypigmented area daily. Facial skin parameters (i.e. melanin index, erythema index) is evaluated at week 0, 1, 2 and 4.

Who can participate

Age range30 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male or Female * Has at least 1 hyperpigmentation spot (size \> 3mm) on either side of the face * 30-60 y/o * Fitzpatrick skin types II-IV * Agrees to use sunscreen SPF50+ and willing to avoid strong sunlight exposure during the study Exclusion Criteria: * Pregnant or lactating * Use of whitening products or treatment within 1 month before this study * Currently using contraceptives * History of allergy to any ingredient in the intervention cream * Has skin conditions which can interfere with the measurement (i.e. severe acne, eczema, herpes simplex) * Severe disease (i.e. immunodeficiency, cancer) * Enrolled in other clinical study within 3 month before this study

What they're measuring

Efficacy of hyperpigmentation reduction property of the intervention

Timeframe: Week 0, 1, 2 and 4

Safefty profile of the intervention

Timeframe: Week 1, 2 and 4

Trial details

NCT IDNCT07133204

SponsorMae Fah Luang University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-30

View on ClinicalTrials.gov More Hyperpigmentation; Melanin trials