Study of Efficacy and Safety of Cream Infused With HuangQin (Root of Scutellaria Baicalensis) Ext… (NCT07133204) | Clinical Trial Compass
CompletedNot Applicable
Study of Efficacy and Safety of Cream Infused With HuangQin (Root of Scutellaria Baicalensis) Extract for the Reduction of Hyperpigmentation
Thailand38 participantsStarted 2025-04-01
Plain-language summary
The aim of this study is to evaluate the efficacy of a topical cream infused with Scutellaria baicalensis extract in reducing hyperpigmentation on the face.
The study is experimental clinical pilot study as a single group pretest-posttest.
A ROAT is conducted 1 week prior to the experiment. Participant apply the cream on the hypigmented area daily. Facial skin parameters (i.e. melanin index, erythema index) is evaluated at week 0, 1, 2 and 4.
Who can participate
Age range
30 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male or Female
* Has at least 1 hyperpigmentation spot (size \> 3mm) on either side of the face
* 30-60 y/o
* Fitzpatrick skin types II-IV
* Agrees to use sunscreen SPF50+ and willing to avoid strong sunlight exposure during the study
Exclusion Criteria:
* Pregnant or lactating
* Use of whitening products or treatment within 1 month before this study
* Currently using contraceptives
* History of allergy to any ingredient in the intervention cream
* Has skin conditions which can interfere with the measurement (i.e. severe acne, eczema, herpes simplex)
* Severe disease (i.e. immunodeficiency, cancer)
* Enrolled in other clinical study within 3 month before this study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Efficacy of hyperpigmentation reduction property of the intervention