Not Yet RecruitingNot Applicable

Predicting Biologic Therapy Success in Ulcerative Colitis Using Intestinal Ultrasound and Fat Assessment

200 participantsStarted 2026-01-01

Plain-language summary

Our study aimed to detecting biological therapy effectiveness in UC patients using visceral fat assessment

Who can participate

Age range18 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Any patient above age of 18 years old and diagnosed to have active UC through * Clinical features: rectal bleeding, with frequent stools and mucous discharge from the rectum. Some patients also describe tenesmus. The onset is typically insidious. * Endoscopic findings include the following; loss of vascular pattern, Granular and fragile mucosa, friability, ulcerations, erosions, pseudo-polyposis. Exclusion Criteria: * Patients with UC who are under age of 18 years old. * Pregnancy. * Previous colectomy. * Patient refuse to participate in the study

What they're measuring

Change in Visceral Adipose Tissue Volume Measured by abdominal and pelvic CT examination from Baseline to month 6

Timeframe: Baseline (pre-treatment) and after induction dose (typically 6 month post-initiation of biological therapy) by abdominal and pelvic CT examination

Effectiveness of Biological Therapy in UC Patients Based on Changes in Visceral Adipose Tissue (VAT) by abdominal and pelvic CT examination

Timeframe: Baseline (pre-treatment) and after induction dose (typically 6 month post-initiation of biological therapy)

Trial details

NCT IDNCT07126015

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-09-01

Contact for this trial

Amira M Abdelmawgod, MD, Assuit University

+201012760437 amiramohmad60@gmail.com

View on ClinicalTrials.gov More Predicting Biologics Success Via VAT Assessment trials