Efficacy of Bioactive Glass vs. Xenograft in Maxillary Sinus Augmentation (NCT07125846) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Efficacy of Bioactive Glass vs. Xenograft in Maxillary Sinus Augmentation
20 participantsStarted 2025-10-15
Plain-language summary
This randomized controlled study aims to evaluate the clinical, radiographic, and histologic efficacy of using bioactive glass bone graft (UNIGRAFT by Biomed Inc., USA) compared to a conventional xenograft in maxillary sinus augmentation procedures. A total of 20 patients classified as SA4 according to the Misch classification will be enrolled and randomly allocated into two groups. Outcomes will be assessed using Cone Beam Computed Tomography (CBCT) for vertical bone gain and, where applicable, histologic analysis. The study is conducted at the Faculty of Dentistry, Suez Canal University.
Who can participate
Age range
20 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients requiring maxillary sinus floor augmentation for dental implant placement.
* Residual alveolar bone height ≤ 4 mm in posterior maxilla (SA4 classification).
* Age between 20 to 65 years.
* Good general health and able to attend scheduled follow-up visits.
* Signed written informed consent.
Exclusion Criteria:
* Presence of systemic conditions that could affect bone healing (e.g., uncontrolled diabetes, osteoporosis).
History of radiotherapy in the head and neck region.
* Heavy smoking (more than 10 cigarettes/day).
* Active sinus pathology or previous sinus surgery.
* Pregnant or breastfeeding women.
* Use of medications affecting bone metabolism (e.g., bisphosphonates or corticosteroids).
* Poor oral hygiene or untreated periodontal disease.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.