Evaluation of the Safety and Performance of Epicare for the Treatment of Periorbital Wrinkles

Inclusion Criteria: * Male or female, 25-65 years of age, in general good health. * Seeking a reduction in the appearance of periorbital wrinkles. * Bilateral and approximately symmetrical periorbital wrinkles with a Fitzpatrick Wrinkle Classification Scale (FWCS) score 4-9, as assessed by the treating investigator. * Fitzpatrick skin type I-V. * Able to understand the study requirements and sign an EC/IRB-approved informed consent form prior to any study procedures. * Willing and able to comply with the treatment and follow-up schedule, pre- and post-treatment instructions, and allow standardized photography. * Willing to withhold additional aesthetic therapies to the treatment area (e.g., fillers, resurfacing procedures) for the entire study duration. Exclusion Criteria: * Known bleeding disorder (e.g., thrombocytopenia, thrombasthenia, von Willebrand's disease). * Immunocompromised or immunosuppressed (e.g., AIDS, HIV, or immunosuppressive therapy). * Planned or recent use of anti-platelets, anti-coagulants, thrombolytics, ACE inhibitors, vitamin E, or anti-inflammatory drugs from 1 week prior to 1 month after treatment. * Systemic corticosteroid or anabolic steroid use within 30 days prior to enrollment (standard inhaled/nasal corticosteroids are permitted). * Use of weight loss medications before or during the study. * History of chronic or recurrent infection or inflammation that would preclude participation. * Severe allergies with history of anaphylaxis. * History …