Pharmacokinetic Study on G1090N (Nitazoxanide) Capsules in Healthy Volunteers

Exclusion criteria

• ✕. Systolic blood pressure (SBP) \<90 mm Hg or \>140 mm Hg;
• ✕. Diastolic blood pressure (DBP) \<50 mm Hg or \>90 mm Hg;
• ✕. Pulse rate \<50 bpm or \>90 bpm; For these parameters, out-of-range values that are not clinically significant (as determined by the Investigator) may be repeated twice during SCR and the subject may be enrolled if at least one repeated value is within the range noted above;
• ✕. PR ≤120 ms or ≥220 ms;
• ✕. QRS \>120 ms;
• ✕. QT interval corrected for heart rate using Fridericia's method ≥450 ms; For these parameters, out-of-range values that are not clinically significant (as determined by the Investigator) may be repeated twice during SCR and Day -1 and the subject may be enrolled if at least 1 repeated value is within the normal ranges noted above; Subjects must also have no sign of any clinically significant irregularity in heart rhythm.