Clinical Transformation of Bone Reconstruction With Autologous Bone Marrow Mesenchymal Stem Cells in Vitro to Repair Avascular Necrosis of Femur Head

Exclusion criteria

• . Based on the researcher's judgment, the subjects had a history of trauma and the injury affected the target hip joint;
• . In the six months prior to screening, there were obvious injuries involving the target hip joint;
• . The subject's femoral head necrosis was due to other diseases affecting the hip joint (such as rheumatoid arthritis, psoriatic arthritis, gouty arthritis, symptomatic cartilage calcification, bone necrosis, active infection), or according to the researcher's judgment, peripheral or central nervous system lesions that might affect the assessment of pain and function of the target hip joint (such as back pain, knee joint disease, intervertebral disc protrusion, sciatic nerve pain, fibromyalgia, diabetic neuropathy, etc.);
• . The femoral head of the target hip joint had obvious necrosis, collapse, joint fusion, etc.;
• . Those who had a history of hip joint replacement, arthroplasty, or other hip joint surgeries, or planned to undergo surgical treatment of any lower limb/hip joint during the study period;
• . The target hip joint had suppurative arthritis or a previous history;
• . The target hip joint had obvious joint effusion;
• . During the screening period, the target hip joint had active joint infection or skin ulceration, infection in the surgical area, or any significant chronic skin disease that might interfere with the surgical procedure;