CompletedNot Applicable

Postoperative Stroke and Epiaortic Ultrasound in CABG

Turkey (Türkiye)150 participantsStarted 2023-12-01

Plain-language summary

This study aims to investigate the incidence of postoperative stroke and neurocognitive impairment in patients undergoing coronary artery bypass grafting (CABG), with or without the use of epi-aortic ultrasound (EAU). Atherosclerosis in the ascending aorta is a known risk factor for perioperative stroke and systemic embolization. The identification of atherosclerotic plaques before manipulation of the ascending aorta is important in minimizing embolic complications. Neurocognitive function will be assessed using the standardized Mini-Mental State Examination (SMMSE) before surgery and within 7 days postoperatively or at discharge. This prospective, observational, case-control study will evaluate the relationship between the presence of atherosclerotic plaques detected by EAU and neurocognitive and neurologic outcomes following CABG surgery.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients scheduled for isolated, elective coronary artery bypass grafting (CABG) * Age 18 years or older Exclusion Criteria: * Illiteracy (inability to read or write) * Visual and/or hearing impairment * Non-citizens/foreign nationals * Refusal to participate in the study * Presence of neuropsychiatric disorders that may affect postoperative cognitive evaluation (e.g., psychosis, dementia, mental retardation) * History of cerebrovascular accident (CVA/stroke) * Preoperative rhythm disturbances associated with stroke risk (e.g., atrial fibrillation, atrial flutter) * Presence of intracardiac thrombus (ventricular or atrial) on preoperative echocardiography * Patients undergoing concomitant cardiac procedures (e.g., valve or aortic surgery) * Emergency CABG surgery * Recent myocardial infarction * Use of intra-aortic balloon pump (IABP) * Redo CABG surgery * Significant carotid stenosis or plaque detected on preoperative carotid Doppler ultrasonography * Chronic renal failure and/or liver failure

What they're measuring

Incidence of Postoperative Stroke

Timeframe: Within 10 days postoperatively

Trial details

NCT IDNCT07101393

SponsorAtaturk University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-12-01